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Tested this out yesterday.  Didn't have any issues and was able to complete the game without any problems.

As for the glitched spots in the randomized crystal corridors, they really shouldn't be too much of a problem.  I've only had issues when it has been the first corridor and Crawdaddy is the boss.  But even then I've almost always been able to work around it.

I mean just not having a key to get into whatever the next area is.  It's possible Corridor 4 had the key I needed.

I believe the main one I played through was "Rambo".  Aside from the no shops and improper key issues, it was fine.  I used a password generator to progress and as far as I could tell, the labyrinths and flight sequences were fine.